what causes diabetes

Results for "mutations cause diabetes"

Permanent neonatal diabetes mellitus More severe mutations in the KCNJ11 gene can cause early-onset diabetes which does not respond to the sulfonylurea drugs, as well as a syndrome of developmental delay and neurological features called the DEND syndrome.

Transcription factor Diabetes A rare form of diabetes called MODY (Maturity onset diabetes of the young) can be caused by mutations in hepatocyte nuclear factors (HNFs) or insulin promoter factor-1 (IPF1/Pdx1).

Maturity onset diabetes of the young Maturity onset diabetes of the young (MODY) refers to any of several hereditary forms of diabetes caused by mutations in an autosomal dominant gene (sex independent, i.e. inherited from any of the parents) disrupting insulin production.

Glucokinase Mutations of the gene for this enzyme can cause unusual forms of diabetes or hypoglycemia.

MODY 2 A form of permanent neonatal diabetes has been caused by homozygous mutations in the GCK gene.

ATP-sensitive potassium channel "[Expression error: Missing operand for > Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes.]".

Results for "drugs caused diabetes"

Eli Lilly controversies But Lilly was concerned that Zyprexa’s sales would be hurt if the company was more forthright about the fact that the drug might cause unmanageable weight gain or diabetes, according to the documents, which cover the period 1995 to 2004.

Adverse effect Diabetes caused by atypical antipsychotic medications (neuroleptic psychiatric drugs)

Olanzapine But Lilly was concerned that Zyprexa’s sales would be hurt if the company was more forthright about the fact that the drug might cause unmanageable weight gain or diabetes, according to the documents, which cover the period 1995 to 2004.

Adverse drug reaction Diabetes caused by atypical antipsychotic medications (neuroleptic psychiatric drugs)

Results for "resistance caused diabetes"

Nutrition The state of obesity clearly contributes to insulin resistance, which in turn can cause type 2 diabetes.

Malnutrition The state of obesity clearly contributes to insulin resistance, which in turn can cause type 2 diabetes.

Human nutrition The state of obesity clearly contributes to insulin resistance, which in turn can cause type 2 diabetes.

Results for "treatment caused diabetes"

Michael Somogyi He took a special interest in diabetic patients and in 1938, at a meeting of the medical society in St. Louis to the theme of “unstable, severe diabetic patients”, Somogyi first presented his theory that insulin treatment in itself might cause unstable diabetes.

Acromegaly In rare cases, octreotide treatment can cause diabetes.

Results for "medications caused diabetes"

Adverse effect Diabetes caused by atypical antipsychotic medications (neuroleptic psychiatric drugs)

Adverse drug reaction Diabetes caused by atypical antipsychotic medications (neuroleptic psychiatric drugs)

Results for "combinations cause diabetes"

Monogenic diabetes In contrast to monogenic diabetes, the more common forms of type 1 and type 2 diabetes are caused by more complicated combinations of multiple genes or environmental factors, not all of which have been identified.

Results for "response caused diabetes"

Juvenile Diabetes Research Foundation Autoimmunity: A key part of JDRF's research is aimed at stopping or reversing the immune system response that causes diabetes: the attack on insulin-secreting cells in the pancreas.

Results for "organs cause diabetes"

Natural diabetes treatments These are the organs that cause diabetes or may be affected by long term of high blood sugar.

Results for "factor caused diabetes"

Transcription factor Diabetes A rare form of diabetes called MODY (Maturity onset diabetes of the young) can be caused by mutations in hepatocyte nuclear factors (HNFs) or insulin promoter factor-1 (IPF1/Pdx1).

Results for "alloxan caused diabetes"

Alloxan One study suggests that alloxan does not cause diabetes in humans.

Results for "fats cause diabetes"

French paradox Trans fats are well known to cause diabetes, heart disease and macular eye disease.

Results for "signals cause diabetes"

University of Pittsburgh School of Medicine The following fields are currently under investigation: epithelial cell biology including investigating the devastating effects of impaired salt transport in inherited diseases such as cystic fibrosis; the intracellular transduction of signals that cause diabetes; identification of the mechanisms of cardiac arrhythmias; the mechanisms by which membranes and cargo are transported into and through the cell; water transport and barrier epithelia and on the biology of ion channels; and chromatin structure and dynamics as well as the study of dystrophin to develop novel treatments for muscular dystrophy.

Results for "apoptosis causes diabetes"

Bcl-2 The autoimmune disease, type 1 diabetes can be caused by defective apoptosis, which leads to aberrant T cell AICD and defective peripheral tolerance.

Results for "onset caused diabetes"

IPEX syndrome Early age onset of this disease in males causes severe enlargement of the secondary lymphoid organs, insulin dependent diabetes, eczema, food allergies, and infections.

Results for "lack causes diabetes"

Frederick Banting The work of Naunyn, Minkowski, Opie, Schafer, and others had indicated that diabetes was caused by lack of a protein hormone secreted by the Islets of Langerhans in the pancreas.

Results for "variants cause diabetes"

Hepatocyte nuclear factors Variants of the genes can cause several relatively rare forms of MODY, an inherited, early onset form of diabetes.

Results for "diseases cause diabetes"

Diabetes mellitus Diseases associated with excessive secretion of insulin-antagonistic hormones can cause diabetes (which is typically resolved once the hormone excess is removed).

Results for "effects cause diabetes"

Gene therapy Unfortunately, some of the most commonly occurring disorders, such as heart disease, high blood pressure, Alzheimer's disease, arthritis, and diabetes, are caused by the combined effects of variations in many genes.

Results for "activate causes diabetes"

Permanent neonatal diabetes mellitus A newly identified and potentially treatable form of monogenic diabetes is the neonatal diabetes caused by activating mutations of the KCNJ11 gene, which codes for the Kir6.2 subunit of the beta cell KATP channel.

Results for "pancreas causes diabetes"

Pancreas transplantation In the event of rejection of the new pancreas which would quickly cause life-threatening diabetes, the recipient could not survive without the native pancreas still in place.

Results for "vaccination causes diabetes"

Vaccine controversy These include theories that vaccination can cause sudden infant death syndrome, epileptic seizures, allergies, multiple sclerosis, and autoimmune diseases such as type 1 diabetes, as well as theories that vaccinations can transmit bovine spongiform encephalopathy, Hepatitis C virus, and HIV.

Results for "lifespan causes diabetes"

Obesity in Mexico These additional health problems can lead to shortening the lifespan of Mexicans by a considerable amount of years compared to an individual with a healthy weight and may cause diabetes which can lead to premature death.

Results for "glucocorticoids cause diabetes"

Steroid diabetes The most common glucocorticoids which cause steroid diabetes are prednisone and dexamethasone given systemically in "pharmacologic doses" for days or weeks.